Thanks to elainsor
for the information that George Street as was, is:
"now O'Connell Street, the building in the foreground is where Roches Stores was until recently . The building with the clock is where Penney's now stands.
And bringing us right up to date is info from DannyM8
that Roches Stores is now Debenhams
Date: Circa 1890?
NLI Ref.: L_ROY_05290
Owner: National Library of Ireland on The Commons
Source: Flickr Commons